Henderson Island

David Willis Wilson Henderson, 1903-1968.

Virginia Henderson and her timeless writings.

This paper provides a reflection on the written works of Miss Virginia Avenel Henderson. Miss Henderson is a nurse, a scientist, an artist and a quintessential human being--all traits which informed her written output. Nursing practice, research and education were all subjects of her extensive chronicle. The four-volume Nursing Studies Index is her contribution to nursing research. The Index wa...

Neonatology on the Web: Henderson 1928

There are probably no procedures in medical practice which are so nearly the same as those of the dark ages, or which have as yet been influenced so little by modern scientific knowledge, as those of the midwife or obstetrician in dealing with a nonbreathing new-born child. Perhaps an excuse may be found in the statements still contained in textbooks of physiology and obstetrics regarding the q...

Efficient computation for Whittaker-Henderson smoothing

Efficient algorithms that compute both the estimates and the generalized cross-validation score for the problem of Whittaker– Henderson smoothing are presented. Algorithm efficiency results from carefully exploiting the problem’s rich structure to reduce execution time and memory use. The algorithms are much faster than existing ones, and use significantly less memory. MATLAB M-files are includ...

pKa values in solubility determination using the Henderson- Hasselbalch equation

Alex Avdeef [1] and Samuel Yalkowsky [2] have independently studied the solubility and ionization properties of an investigational drug (NSC-639829). In the study conducted by Avdeef and coworkers, the pKa value derived from Henderson-Hasselbalch (HH) equation was 4.70, which was different from the value of 3.76 as determined experimentally by the Yasuda-Shedlovsky plot using the pKa values obt...